Dr Sander W. van der Laan, PhD

Dr Sander W. van der Laan is a junior postdoctoral fellow in the Laboratory of Experimental Cardiology within the Circulatory Health Program at the University Medical Center Utrecht and University of Utrecht. His research interest is in the genetic and epigenetic causes of carotid and coronary atherosclerosis underlying ischemic stroke (IS) and coronary artery disease (CAD).

He is currently working on integrating Bayesian fine-mapping methodology, expression and methylation quantitative trait loci (QTL) analyses in circulating cells and atherosclerotic tissues, and genome-wide association studies (GWAS) of plaque and serum biomarkers as well as plaque characteristics based on high-through imaging of histological slides. As means of integrating these biological layers he applies Mendelian Randomisation methods to infer causal genes, proteins, networks and biomarkers underlying IS and CAD.

He actively contributes to the International Stroke Genetics Consortium. In addition, he makes contributions to international consortia, including GENIUS-CHD, GIANT, GLGC, GoDMC, 1Million Hearts, and various others.